when coming from the north exit at Valdichiana (distance from the toll gate around 15 km) and follow signs for Torrita di Siena and after for Montepulciano;
when coming from the south exit at Chiusi - Chianciano Terme and follow signs for Chianciano Terme and after for Montepulciano (distance from the toll gate around 18 km).
Siena - Perugia Highway:
exit at Sinalunga when coming from Siena and follow signs for Torrita di Siena and after for Montepulciano, (distance around 22 km);
exit at Bettolle when coming from Perugia and follow signs for Torrita di Siena and after for Montepulciano, (distance around 18 km)
follow the signs for San Quirico d'Orcia, Pienza and Montepulciano when arriving from Siena(distance from Siena around 60 km, from San Quirico d'Orcia around 25 km and from Pienza around 12 km);
follow the signs for Monticchiello and Montepulciano when arriving from Rome for Roma making a diversion at Gallina (distance from Roma around 220 km, from Gallina around 40 km).
timetable on www.sienamobilita.it, www.trainspa.it
Chiusi - Chianciano Terme Station: bus service to Montepulciano. In around 50 minutes you will be in Montepulciano.
Florence Airport: 120 km
Pisa Airport: 150 km
Roma Fiumicino Airport: 250 km